Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654283 | 1.00 | PKM (0.53) | PKMALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL1305714 | 0.79 | ALDH1A1 (0.49) | PKMALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL1305718 | 0.79 | ALDH1A1 (0.49) | PKMALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL29413047 | 0.77 | ALDH1A1 (0.57) | PKMALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL501876 | 0.77 | ALDH1A1 (0.57) | PKMALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL11656158 | 0.76 | ALDH1A1 (0.56) | PKMALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL4206945 | 0.76 | ALDH1A1 (0.56) | PKMALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL143766 | 0.74 | ALDH1A1 (0.59) | PKMALDH1A1KDM4EMAPTKMT2A | |
| Bromide SCHEMBL20984528 | 0.72 | FABP4 (0.57) | PKMALDH1A1KDM4EMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL1522753 | 0.72 | FABP4 (0.57) | PKMALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217216-A1 | FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS | Scolr Pharma, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009061805-A1 | FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS | SCOLR PHARMA, INC. (US) | 2009-05-14 | — | — | WO | disclosed |