Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367074 | 0.93 | LMNA (0.39) | PTGER4MCL1ADAM17ALDH1A1MEN1 | |
| SCHEMBL365603 | 0.90 | TSHR (0.38) | ADAM17ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL366344 | 0.89 | PSEN1 (0.39) | MCL1ADAM17ALDH1A1KDM4EMEN1 | |
| SCHEMBL364894 | 0.86 | PSEN1 (0.39) | PTGER4ADAM17ALDH1A1KDM4EMEN1 | |
| SCHEMBL366151 | 0.86 | EGFR (0.45) | MCL1PTPN7KDM4EMEN1LMNA | |
| SCHEMBL364828 | 0.86 | MCL1 (0.37) | MCL1ADAM17 | |
| SCHEMBL365498 | 0.86 | KMT2A (0.45) | P4HTMPTGER4MCL1PTPN1MET | |
| SCHEMBL367542 | 0.85 | PSEN1 (0.42) | MCL1ADAM17ARPTPN1ALDH1A1 | |
| SCHEMBL364900 | 0.82 | PSEN1 (0.39) | ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL366032 | 0.81 | PSEN1 (0.38) | ALDH1A1KDM4EMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |