Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655009 | 1.00 | MTNR1A (0.58) | MTNR1AMTNR1BLDHAKDM4EALDH1A1 | |
| SCHEMBL18260742 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BSMN1; SMN2TDP1SLC6A4 | |
| SCHEMBL11212797 | 0.82 | MTNR1A (0.53) | MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL13033017 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BLDHASMN1; SMN2 | |
| SCHEMBL10958161 | 0.78 | LDHA (0.55) | MTNR1AMTNR1BLDHAKDM4EALDH1A1 | |
| SCHEMBL21991548 | 0.75 | LDHA (0.47) | MTNR1AMTNR1BLDHAKDM4EALDH1A1 | |
| SCHEMBL16611798 | 0.75 | MTNR1A (0.48) | MTNR1AMTNR1B | |
| SCHEMBL2549352 | 0.75 | CYP1A2 (0.46) | ALDH1A1SMN1; SMN2LMNASLC6A4CYP2D6 | |
| SCHEMBL3579103 | 0.74 | MTNR1A (0.57) | MTNR1AMTNR1BSLC6A4PPARGPPARA | |
| SCHEMBL3579104 | 0.74 | MTNR1A (0.57) | MTNR1AMTNR1BSLC6A4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217578-A1 | [1,2,4]TRIAZOLO[1,5-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS AND THEIR USE | Cancer Research Technology Limited (GB) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009047514-A1 | [1,2,4]TRIAZOLO[1,5-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-04-16 | — | — | WO | disclosed |