Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 4/20 | 0.42 |
| ▸ | FLT4 | P35916 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365931 | 0.90 | MAPT (0.47) | TP53MAPTHPGDFLT1FLT4 | |
| SCHEMBL366382 | 0.85 | HPGD (0.38) | KMT2AMEN1POLBTP53RECQL | |
| SCHEMBL366977 | 0.85 | SCN9A (0.46) | KMT2AMEN1MAPTHPGD | |
| SCHEMBL365520 | 0.83 | POLB (0.46) | KMT2AMEN1POLBCYP2C9PTGS2 | |
| SCHEMBL365440 | 0.83 | MAPT (0.41) | KMT2AMEN1CYP2C9TP53MAPT | |
| SCHEMBL366252 | 0.80 | ALDH1A1 (0.39) | KMT2AMEN1CYP2C9TP53MAPT | |
| SCHEMBL366209 | 0.79 | HPGD (0.46) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL364820 | 0.79 | KMT2A (0.46) | KMT2AMEN1POLBCYP2C9PTGS2 | |
| SCHEMBL364815 | 0.78 | PTPN1 (0.39) | KMT2AMEN1CYP2C9TP53MAPT | |
| SCHEMBL367568 | 0.78 | ALDH1A1 (0.44) | KMT2AMEN1TP53MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |