Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366382 | 0.93 | HPGD (0.38) | HPGDP4HTMPTPN1PTGER4MAPT | |
| SCHEMBL366059 | 0.90 | S1PR3 (0.38) | HPGDP4HTMMAPTKMT2AALDH1A1 | |
| SCHEMBL365440 | 0.89 | MAPT (0.41) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL366252 | 0.86 | ALDH1A1 (0.39) | HPGDPTPN1PTGER4MAPTMEN1 | |
| SCHEMBL366977 | 0.85 | SCN9A (0.46) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL364815 | 0.84 | PTPN1 (0.39) | HPGDPTPN1PTGER4MAPTMEN1 | |
| SCHEMBL366210 | 0.83 | HPGD (0.47) | HPGDP4HTMPTPN1PTGER4MAPT | |
| SCHEMBL365519 | 0.79 | KMT2A (0.45) | HPGDMAPTMEN1KMT2AGAA | |
| SCHEMBL365498 | 0.79 | KMT2A (0.45) | HPGDP4HTMPTPN1PTGER4MAPT | |
| SCHEMBL366875 | 0.78 | EGFR (0.42) | HPGDMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |