SCHEMBL365524

SCHEMBL365524

NOBOc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.41
TSHR P16473 1/20 0.41
CA4 P22748 1/20 0.38
MAOA P21397 1/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
KCNA3 P22001 1/20 0.35
MAOB P27338 1/20 0.33
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
IDO1 P14902 1/20 0.33
AGXT P21549 1/20 0.32
NR1H2 P55055 1/20 0.32
BAX Q07812 1/20 0.32
SOS1 Q07889 1/20 0.31
PARP10 Q53GL7 1/20 0.31
SCN4A P35499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8885 0.83 LTA4H (0.50) LTA4HTSHRCA4MAOACA1
Hydrochloric Acid SCHEMBL693111 0.80 LTA4H (0.47) LTA4HTSHRCA4MAOACA1
SCHEMBL29544396 0.78 LTA4H (0.45) LTA4HTSHRCA4MAOACA1
SCHEMBL4735958 0.74 CA4 (0.50) LTA4HTSHRCA4MAOACA1
SCHEMBL449851 0.74 LTA4H (0.63) LTA4HTSHRMAOACA1CA2
SCHEMBL852456 0.74 LTA4H (0.41) LTA4HTSHRCA4MAOACA1
SCHEMBL4531186 0.74 CA4 (0.43) LTA4HTSHRCA4MAOACA1
SCHEMBL4697871 0.74 LTA4H (0.41) LTA4HTSHRCA4MAOACA1
SCHEMBL1162702 0.74 LTA4H (0.41) LTA4HTSHRCA4MAOACA1
SCHEMBL28166668 0.73 TAAR1 (0.41) LTA4HTSHRCA4MAOATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111788484-B Method for stabilizing protein contained in sample, solution for stabilizing protein contained in sample 荣研化学株式会社 2024-11-19 CN claimed
EP-4421168-A2 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE Halozyme, Inc. (US) 2024-08-28 EP claimed
EP-4269578-B1 SOLUBLE HYALURONIDASE COMPOSITION HALOZYME INC (US) 2024-06-05 EP claimed
EP-4269578-A1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE Halozyme, Inc. (US) 2023-11-01 EP claimed
CN-111774111-B Micro-fluidic chip for detecting glycosylated hemoglobin and detection method thereof 上海佰芯生物科技有限公司 2023-04-11 CN claimed
CN-113136020-B Water-based polyurethane polymer and preparation method thereof, single-component water-based polyurethane waterproof coating and preparation method and application thereof 万华化学集团股份有限公司 2022-08-05 CN claimed
CN-113136020-A Water-based polyurethane polymer and preparation method thereof, single-component water-based polyurethane waterproof coating and preparation method and application thereof 万华化学集团股份有限公司 2021-07-20 CN claimed
CN-111774111-A Micro-fluidic chip for detecting glycosylated hemoglobin and detection method thereof 上海佰芯生物科技有限公司 2020-10-16 CN claimed
US-9493652-B2 Polymeric film composition for non-enzymatic glucose sensor and non-enzymatic glucose sensor including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-11-15 US claimed
US-20150144486-A1 POLYMERIC FILM COMPOSITION FOR NON-ENZYMATIC GLUCOSE SENSOR AND NON-ENZYMATIC GLUCOSE SENSOR INCLUDING THE SAME INSTITUTE FOR RESEARCH & INDUSTRY COOPERATION, PNU (KR) 2015-05-28 US claimed
EP-2268805-B1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE HALOZYME INC (US) 2015-05-06 EP claimed
US-8702931-B2 Low cost electrochemical disposable sensor for measuring glycated hemoglobin INDIAN INSTITUTE OF SCIENCE (IN) 2014-04-22 US claimed
US-20120261257-A1 LOW COST ELECTROCHEMICAL DISPOSABLE SENSOR FOR MEASURING GLYCATED HEMOGLOBIN INDIAN INSTITUTE OF SCIENCE (IN) 2012-10-18 US claimed
US-8187855-B2 Large-scale production of soluble hyaluronidase HALOZYME, INC. (US) 2012-05-29 US claimed
US-20110053247-A1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE HALOZYME, INC. 2011-03-03 US claimed
EP-2268805-A1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE Halozyme, Inc. (US) 2011-01-05 EP claimed
WO-2009111066-A1 LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE HALOZYME, INC. (US) 2009-09-11 WO claimed
US-4562251-A Agarose derivatives of amino phenyl boronic acid AMICON CORPORATION (US) 1985-12-31 US claimed
US-20250222078-A1 MODIFIED HYALURONIDASES AND USES IN TREATING HYALURONAN-ASSOCIATED DISEASES AND CONDITIONS HALOZYME, INC. (US) 2025-07-10 US disclosed
US-4562251-A Agarose derivatives of amino phenyl boronic acid AMICON CORPORATION (US) 1985-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250222078-A1 MODIFIED HYALURONIDASES AND USES IN TREATING HYALURONAN-ASSOCIATED DISEASES AND CONDITIONS CD44, HPSE, ENGASE LTA4H 165/4885TSHR 2946/4885CA4 395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.