SCHEMBL852456

SCHEMBL852456

BrOBOc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.41
TSHR P16473 1/20 0.41
CA4 P22748 1/20 0.38
KCNA3 P22001 1/20 0.35
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
NR1H2 P55055 1/20 0.32
BAX Q07812 1/20 0.32
MAOA P21397 1/20 0.32
TDP1 Q9NUW8 3/20 0.31
ALDH1A1 P00352 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
RECQL P46063 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
SRC P12931 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8885 0.83 LTA4H (0.50) LTA4HTSHRCA4KCNA3CA5A
Hydrochloric Acid SCHEMBL693111 0.80 LTA4H (0.47) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL29544396 0.78 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL21274278 0.75 LTA4H (0.38) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL4735958 0.74 CA4 (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1162702 0.74 LTA4H (0.41) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL449851 0.74 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL4697871 0.74 LTA4H (0.41) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL4531186 0.74 CA4 (0.43) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL365524 0.74 LTA4H (0.41) LTA4HTSHRCA4KCNA3CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1923385-B1 Iridium complex, carbazole derivatives and copolymer having the same KWANGJU INST SCI & TECH (KR) 2009-05-27 EP claimed
US-20080177084-A1 IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-24 US claimed
EP-1923385-A1 Iridium complex, carbazole derivatives and copolymer having the same Gwangju Institute of Science and Technology (KR) 2008-05-21 EP claimed
EP-3056498-B1 DIAZADIBENZOFURANE AND DIAZADIBENZOTHIOPHENE DERIVATIVES AND THEIR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG SDI CO LTD (KR) 2018-09-19 EP disclosed
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-08-18 US disclosed
EP-3056498-A1 DIAZADIBENZOFURANE AND DIAZADIBENZOTHIOPHENE DERIVATIVES AND THEIR USE IN ORGANIC OPTOELECTRONIC DEVICES Samsung SDI Co., Ltd. (KR) 2016-08-17 EP disclosed
EP-2432556-A1 PROTEASE INHIBITORS Orion Corporation (FI) 2012-03-28 EP disclosed
WO-2010133748-A1 PROTEASE INHIBITORS ORION CORPORATION (FI) 2010-11-25 WO disclosed
US-7727690-B2 Iridium complex, carbazole derivatives and copolymer having the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-06-01 US disclosed
EP-1923385-B1 Iridium complex, carbazole derivatives and copolymer having the same KWANGJU INST SCI & TECH (KR) 2009-05-27 EP disclosed
US-20080177084-A1 IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-24 US disclosed
EP-1923385-A1 Iridium complex, carbazole derivatives and copolymer having the same Gwangju Institute of Science and Technology (KR) 2008-05-21 EP disclosed
EP-1414955-A4 COMPOSITIONS FOR ENHANCED CATALYZED REPORTER DEPOSITION PERKINELMER LIFE SCIENCES INC (US) 2004-10-06 EP disclosed
EP-1414955-A2 COMPOSITIONS FOR ENHANCED CATALYZED REPORTER DEPOSITION Perkinelmer Life Sciences, Inc. (US) 2004-05-06 EP disclosed
WO-2003002733-A2 COMPOSITIONS FOR ENHANCED CATALYZED REPORTER DEPOSITION PERKINELMER LIFE SCIENCES, INC. (US) 2003-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177084-A1 IRIDIUM COMPLEX, CARBAZOLE DERIVATIVES AND COPOLYMER HAVING THE SAME INTS9, HIRIP3, HELZ LTA4H 1977/4885TSHR 3961/4885CA4 2509/4885
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OXER1, OCIAD1 LTA4H 416/4885TSHR 3427/4885CA4 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.