Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BAX | Q07812 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885 | 0.83 | LTA4H (0.50) | CA4LTA4HTSHRNR1H2BAX | |
| Hydrochloric Acid SCHEMBL693111 | 0.80 | LTA4H (0.47) | CA4LTA4HTSHRNR1H2BAX | |
| SCHEMBL4531186 | 0.79 | CA4 (0.43) | CA4LTA4HTSHRNR1H2BAX | |
| SCHEMBL29544396 | 0.78 | LTA4H (0.45) | CA4LTA4HTSHRNR1H2BAX | |
| SCHEMBL28591821 | 0.77 | KMT2A (0.41) | CA4TSHRHPGDSMN1; SMN2 | |
| SCHEMBL8100627 | 0.75 | CA4 (0.41) | CA4LTA4HTSHRKCNA3MAOB | |
| SCHEMBL449851 | 0.74 | LTA4H (0.63) | LTA4HTSHRNR1H2BAXCA1 | |
| SCHEMBL4697871 | 0.74 | LTA4H (0.41) | CA4LTA4HTSHRNR1H2BAX | |
| SCHEMBL1162702 | 0.74 | LTA4H (0.41) | CA4LTA4HTSHRNR1H2BAX | |
| SCHEMBL365524 | 0.74 | LTA4H (0.41) | CA4LTA4HTSHRNR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544167-B2 | Compounds as stimuli-responsive probes, methods and applications thereof | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2020-01-28 | — | — | US | claimed |
| US-20180251478-A1 | COMPOUNDS AS STIMULI-RESPONSIVE PROBES, METHODS AND APPLICATIONS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2018-09-06 | — | — | US | claimed |
| EP-3341384-A1 | COMPOUNDS AS STIMULI-RESPONSIVE PROBES, METHODS AND APPLICATIONS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2018-07-04 | — | — | EP | claimed |
| WO-2017033163-A1 | COMPOUNDS AS STIMULI-RESPONSIVE PROBES, METHODS AND APPLICATIONS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2017-03-02 | — | — | WO | claimed |
| CN-119546585-A | Preparation, application and application of indole compound | 上海济煜医药科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| US-10544167-B2 | Compounds as stimuli-responsive probes, methods and applications thereof | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2020-01-28 | — | — | US | disclosed |
| US-20180251478-A1 | COMPOUNDS AS STIMULI-RESPONSIVE PROBES, METHODS AND APPLICATIONS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2018-09-06 | — | — | US | disclosed |
| EP-3341384-A1 | COMPOUNDS AS STIMULI-RESPONSIVE PROBES, METHODS AND APPLICATIONS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017033163-A1 | COMPOUNDS AS STIMULI-RESPONSIVE PROBES, METHODS AND APPLICATIONS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2017-03-02 | — | — | WO | disclosed |
| US-20140155305-A1 | THICKENING OF FLUIDS | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2014-06-05 | — | — | US | disclosed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2007123941-A2 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | WYETH (US) | 2007-11-01 | — | — | WO | disclosed |
| EP-1244446-B1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2006-11-02 | — | — | EP | disclosed |
| US-6858630-B2 | Naphthimidazole derivatives and their use as thrombopoietin mimetics | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030083361-A1 | Naphtho(1,2-d)imidazole derivatives; treating thrombocytopenia | SMITHKLINE BEECHAM CORPORATION | 2003-05-01 | — | — | US | disclosed |
| EP-1244446-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1244446-A1 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001039773-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544167-B2 | Compounds as stimuli-responsive probes, methods and applications thereof | ROS1, SQOR, NOX4 | CA4 1989/4885LTA4H 2053/4885TSHR 2305/4885 |
| US-20030083361-A1 | Naphtho(1,2-d)imidazole derivatives; treating thrombocytopenia | MPL, THPO, TPO | CA4 4630/4885LTA4H 3640/4885TSHR 122/4885 |
| US-20180251478-A1 | COMPOUNDS AS STIMULI-RESPONSIVE PROBES, METHODS AND APPLICATIONS THEREOF | ROS1, SQOR, NOX4 | CA4 1989/4885LTA4H 2053/4885TSHR 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.