Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.39 |
| ▸ | S100A10 | P60903 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16246531 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL16246497 | 0.87 | ANXA2 (0.41) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL16246338 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL16246417 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL16387391 | 0.76 | FLT3 (0.55) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL16338373 | 0.75 | CFTR (0.51) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL28156744 | 0.73 | MAPT (0.37) | ALDH1A1MAPTUSP2HPGDHSD17B10 | |
| SCHEMBL16263887 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1GAAKMT2A | |
| (Phenylsulfonyl)Benzene SCHEMBL8958296 | 0.68 | HTR6 (0.74) | ALDH1A1MEN1KMT2AHPGDNPSR1 | |
| (Phenylsulfonyl)Benzene SCHEMBL28297601 | 0.68 | HTR6 (0.74) | ALDH1A1MEN1KMT2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |