Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364999 | 0.83 | ALDH1A1 (0.60) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL367568 | 0.80 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL364541 | 0.79 | KDM4E (1.00) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL365547 | 0.78 | ALDH1A1 (0.45) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL366875 | 0.78 | EGFR (0.42) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL367329 | 0.77 | BAZ2B (0.47) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL366735 | 0.77 | HTT (0.48) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| Potassium Ion SCHEMBL364866 | 0.76 | MAPT (0.40) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL365090 | 0.76 | ALDH1A1 (0.68) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL365639 | 0.75 | KMT2A (0.66) | KMT2AALDH1A1MEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |