Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365000 | 0.82 | HTT (0.42) | ALDH1A1MAPK1STAT3KMT2AMEN1 | |
| SCHEMBL367569 | 0.79 | SRC (0.46) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL365546 | 0.78 | KMT2A (0.64) | ALDH1A1MAPK1STAT3KMT2AMEN1 | |
| SCHEMBL364542 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPK1STAT3KMT2AMEN1 | |
| SCHEMBL366876 | 0.77 | EGFR (0.44) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL366736 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL367330 | 0.75 | EGFR (0.46) | ALDH1A1KMT2AKDM4EHPGDEGFR | |
| Potassium Ion SCHEMBL364867 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL365640 | 0.74 | KMT2A (0.43) | ALDH1A1MAPK1STAT3KMT2AMEN1 | |
| SCHEMBL366922 | 0.74 | L3MBTL1 (0.62) | ALDH1A1MAPK1STAT3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |