SCHEMBL365563

SCHEMBL365563

O=C(O)c1c(F)ccc(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.47
CES1 P23141 6/20 0.47
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA4 P22748 2/20 0.41
BCHE P06276 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ASPH Q12797 1/20 0.39
KDM8 Q8N371 1/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CAT P04040 1/20 0.38
ALDH1A1 P00352 1/20 0.37
ALB P02768 1/20 0.37
FABP4 P15090 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31258574 1.00 CES2 (0.47) CES2CES1CA1CA2CA4
SCHEMBL30048528 0.86 CES2 (0.50) CES2CES1CA1CA2KDM4E
SCHEMBL3309453 0.86 CES2 (0.50) CES2CES1CA1CA2KDM4E
SCHEMBL3378267 0.84 CES2 (0.43) CES2CES1CA1CA2BCHE
Bicarbonate SCHEMBL7829383 0.84 CES2 (0.38) CES2CES1CA1CA2CA4
SCHEMBL6139209 0.84 CES2 (0.45) CES2CES1CA1CA2CA4
SCHEMBL1467095 0.83 DPP4 (0.50) CES2CES1KDM4EALDH1A1FABP4
SCHEMBL31197230 0.83 HSD17B1 (0.49) CES2CES1CA1CA2KDM4E
SCHEMBL30933127 0.83 CA1 (0.50) CES2CES1CA1CA2CA4
SCHEMBL3308958 0.83 CES2 (0.52) CES2CES1CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4634196-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES Momentive Performance Materials GmbH (DE) 2025-10-22 EP claimed
WO-2024250497-A1 PHOTOELECTRIC DEVICE AND MANUFACTURING METHOD THEREFOR, AND DISPLAY APPARATUS TCL科技集团股份有限公司 2024-12-12 WO claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
WO-2024126692-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2024-06-20 WO claimed
CN-114733578-B Vulcanizing liquid and preparation method and application thereof 中国石油化工股份有限公司 2024-01-05 CN claimed
CN-115181054-A Synthetic method of 3-benzyl indole compound 合肥工业大学 2022-10-14 CN claimed
CN-114733578-A Vulcanizing liquid and preparation method and application thereof 中国石油化工股份有限公司 2022-07-12 CN claimed
CN-111122688-B Fire material evidence identification method for cigarette combustion ash 应急管理部沈阳消防研究所 2022-06-28 CN claimed
CN-113956877-A Preparation of organic fluorine-containing carbon quantum dot with near-infrared excitation/emission property 重庆医科大学 2022-01-21 CN claimed
WO-1999005319-A2 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE, INC. (US) 1999-02-04 WO claimed
EP-0868535-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES Rapigene, Inc. (US) 1998-10-07 EP claimed
EP-0850320-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL DARWIN MOLECULAR CORPORATION (US) 1998-07-01 EP claimed
WO-1997027331-A9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES 1997-10-09 WO claimed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 WO claimed
WO-1997027327-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL RAPIGENE, INC. (US) 1997-07-31 WO claimed
EP-0608713-B1 2,3-Difluoro-6-introbenzonitrile and 2-chloro-5,6-difluorobenzonitrile, process for their preparation and their use in the preparation of 2,3,6-trifluorobenzoic acid HOECHST AG (DE) 1996-12-27 EP claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 EP claimed
US-5478963-A 2,3-difluoro-6-nitrobenzonitrile and 2-chloro-5,6-difluorobenzonitrile-(2,3-difluoro-6-chlorobenzonitrile), process for their preparation and their use for the preparation of 2,3,6-trifluorobenzoic acid HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-26 US claimed
EP-0608713-A1 2,3-Difluoro-6-introbenzonitrile and 2-chloro-5,6-difluorobenzonitrile, process for their preparation and their use in the preparation of 2,3,6-trifluorobenzoic acid HOECHST AKTIENGESELLSCHAFT (DE) 1994-08-03 EP claimed