Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365014 | 0.87 | KDM4E (0.48) | EGFRKMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL365565 | 0.86 | KMT2A (0.52) | KMT2AMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL364207 | 0.83 | EGFR (0.47) | EGFRSRCKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL367283 | 0.83 | RAB9A (0.44) | EGFRSRCKMT2AALDH1A1LMNA | |
| SCHEMBL364969 | 0.81 | KDM4E (0.53) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL367564 | 0.81 | HPGD (0.50) | KMT2ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL365591 | 0.80 | HPGD (0.49) | KMT2ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL366032 | 0.79 | PSEN1 (0.38) | EGFRSRCKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL367201 | 0.79 | EGFR (0.45) | EGFRSRCKDM4EALDH1A1PARP1 | |
| SCHEMBL367764 | 0.79 | EGFR (0.45) | EGFRSRCKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |