Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442648 | 0.81 | NR3C1 (0.60) | NR3C1NR3C2PGR | |
| SCHEMBL5780546 | 0.79 | NR3C2 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL3680907 | 0.79 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL3652051 | 0.78 | NR3C2 (0.65) | NR3C1NR3C2PGR | |
| SCHEMBL3685002 | 0.77 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL3689211 | 0.74 | NR3C2 (0.46) | NR3C1NR3C2 | |
| SCHEMBL291670 | 0.73 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL1932538 | 0.72 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL2751688 | 0.68 | PDE4A (0.53) | — | |
| SCHEMBL3684692 | 0.68 | NR3C2 (0.43) | NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203160-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | Bausch & Lomb Incorporated (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009042377-A1 | PHARMACOLOGICAL ADJUNCTIVE TREATMENT ASSOCIATED WITH GLAUCOMA FILTRATION SURGERY | BAUSCH & LOMB INCORPORATED (US) | 2009-04-02 | — | — | WO | disclosed |