Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686287 | 0.79 | NR3C1 (0.39) | NR3C2NR3C1 | |
| SCHEMBL3652051 | 0.78 | NR3C2 (0.65) | NR3C2NR3C1 | |
| SCHEMBL3684124 | 0.76 | CYP19A1 (0.36) | NR3C2NR3C1 | |
| SCHEMBL4430210 | 0.76 | PDK1 (0.43) | NR3C2KIF11 | |
| SCHEMBL8508741 | 0.74 | KIF11 (0.54) | KIF11 | |
| SCHEMBL3685002 | 0.74 | NR3C1 (0.49) | NR3C2NR3C1 | |
| SCHEMBL4452422 | 0.74 | NR3C1 (0.49) | NR3C2NR3C1KIF11 | |
| SCHEMBL16233081 | 0.73 | LMNA (0.50) | KIF11 | |
| SCHEMBL13413232 | 0.73 | KIF11 (0.46) | KIF11 | |
| SCHEMBL3658752 | 0.72 | NR3C1 (0.34) | NR3C2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| EP-2056799-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING GLAUCOMA OR PROGRESSION THEREOF | Bausch & Lomb Incorporated (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2008027796-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING GLAUCOMA OR PROGRESSION THEREOF | BAUSCH & LOMB INCORPORATED (US) | 2008-03-06 | — | — | WO | disclosed |