Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30302551 | 0.93 | KDM4E (0.50) | KDM4EALDH1A1BACE1EPHX2SCN4A | |
| SCHEMBL3655234 | 0.93 | KDM4E (0.50) | KDM4EALDH1A1BACE1EPHX2SCN4A | |
| SCHEMBL3662373 | 0.82 | ALDH1A1 (0.52) | ALDH1A1PDE10AMETAP2 | |
| SCHEMBL16670698 | 0.79 | KDM4E (0.50) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL5679852 | 0.79 | BACE1 (0.59) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL29639042 | 0.79 | KDM4E (0.50) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL10849169 | 0.79 | KDM4E (0.59) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL20033417 | 0.79 | KDM4E (0.50) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL437476 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1BACE1EPHX2SCN4A | |
| SCHEMBL1721228 | 0.76 | BACE1 (0.50) | KDM4EBACE1EPHX2SCN4APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62033160-A | — | — | None | — | — | JP | disclosed |
| JP-56167671-A | — | — | None | — | — | JP | disclosed |
| WO-2024220556-A2 | HETEROCYCLIC SUMO1 SMALL MOLECULE DEGRADERS AND USE THEREOF | HB THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-105873914-B | Substituted quinoxaline derivatives as pest control agents | 拜耳作物科学股份公司 | 2018-10-19 | — | — | CN | disclosed |
| CN-108191778-A | It treats different things alike the method for preparing 2,3- dichloro-quinoxaline derivatives | 重庆医科大学 | 2018-06-22 | — | — | CN | disclosed |
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| EP-2867221-B1 | CYANOGUANIDINES AND THEIR SUE AS ANTIVIRAL AGENTS. | ABBVIE INC (US) | 2018-01-17 | — | — | EP | disclosed |
| EP-3252045-A1 | CYANOGUANIDINES AND THEIR USE AS ANTIVIRAL AGENTS | AbbVie Inc. (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20090163485-A1 | HETEROARYL DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-06-25 | — | — | US | disclosed |
| US-20090163485-A1 | HETEROARYL DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-06-25 | — | — | US | disclosed |
| EP-0506373-B1 | Cyanoketone derivative and herbicide containing it as an active component | TOKUYAMA CORP (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5234894-A | CARBONYL ACETONITRILE DERIVATIVE AND HERBICIDE CONTAINING IT AS AN ACTIVE COMPONENT | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0506373-A2 | Cyanoketone derivative and herbicide containing it as an active component | TOKUYAMA CORPORATION (JP) | 1992-09-30 | — | — | EP | disclosed |
| JP-S6233160-A | NOVEL BENZOYL COMPOUND | IHARA CHEM IND CO LTD | 1987-02-13 | — | — | JP | disclosed |
| EP-0046468-A1 | Quinoxaline derivatives and herbicidal composition | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-03-03 | — | — | EP | disclosed |
| JP-S56167671-A | QUINOXALINE DERIVATIVE AND HERBICIDE | NISSAN CHEM IND LTD | 1981-12-23 | — | — | JP | disclosed |
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163485-A1 | HETEROARYL DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | HCRTR1, HCRTR2, MTNR1A | KDM4E 3183/4885ALDH1A1 1037/4885BACE1 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.