Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849169 | 0.79 | KDM4E (0.59) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL20033417 | 0.79 | KDM4E (0.50) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL3656007 | 0.79 | KDM4E (0.50) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL5679852 | 0.79 | BACE1 (0.59) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL29639042 | 0.79 | KDM4E (0.50) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL13356634 | 0.75 | BACE1 (0.46) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL23190280 | 0.75 | NOS1 (0.35) | KDM4EPARP1 | |
| SCHEMBL27870455 | 0.75 | KDM4E (0.46) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL13356605 | 0.74 | BACE1 (0.62) | KDM4EBACE1EPHX2SCN4APDE10A | |
| SCHEMBL22346775 | 0.73 | ALDH1A1 (0.56) | KDM4EDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9936700-B2 | Substituted quinoxaline derivatives as pest control agent | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-10 | — | — | US | disclosed |
| EP-3060557-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-31 | — | — | EP | disclosed |
| US-20160227779-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BRETSCHNEIDER, NIKLAS TIM (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160227779-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BRETSCHNEIDER, NIKLAS TIM (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160227779-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BRETSCHNEIDER, NIKLAS TIM (DE) | 2016-08-11 | — | — | US | disclosed |
| WO-2015059088-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BAYER CROPSCIENCE AG (DE) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015059088-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | BAYER CROPSCIENCE AG (DE) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160227779-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES AS PEST CONTROL AGENT | CHRM1, CHRM2, ACHE | KDM4E 1076/4885BACE1 4321/4885EPHX2 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.