Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL434092 | 0.87 | MGAM (0.47) | CYP1A2CA12CA9CNR2MGAM | |
| Sulfuric Acid SCHEMBL29378161 | 0.87 | MGAM (0.47) | CYP1A2CA12CA9CNR2MGAM | |
| Fluoride SCHEMBL28218526 | 0.86 | NCF1 (0.46) | CYP1A2CNR2MGAMALDH1A1PRNP | |
| Sulfuric Acid SCHEMBL31183024 | 0.85 | MGAM (0.46) | CYP1A2CA12CA9CNR2MGAM | |
| Sulfuric Acid SCHEMBL412226 | 0.85 | MGAM (0.46) | CYP1A2CA12CA9CNR2MGAM | |
| Sulfuric Acid SCHEMBL27909567 | 0.85 | MGAM (0.46) | CYP1A2CA12CA9CNR2MGAM | |
| Quinaldine SCHEMBL28214171 | 0.83 | CYP1A2 (0.66) | CYP1A2CA12CA9CNR2MGAM | |
| Sulfuric Acid SCHEMBL412224 | 0.82 | MGAM (0.43) | CYP1A2CA12CA9CNR2MGAM | |
| SCHEMBL84064 | 0.81 | NCF1 (0.52) | CYP1A2CA12CA9CNR2MGAM | |
| SCHEMBL29376435 | 0.81 | NCF1 (0.52) | CYP1A2CA12CA9CNR2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217204-B1 | COMPOSITIONS FOR THE TOPICAL PROTECTION OF THE OCULAR TISSUES FROM THE DAMAGING EFFECTS OF ULTRAVIOLET RADIATIONS | BRUSCHETTINI SRL (IT) | 2017-06-28 | — | — | EP | disclosed |
| EP-2217204-A2 | COMPOSITIONS FOR THE TOPICAL PROTECTION OF THE OCULAR TISSUES FROM THE DAMAGING EFFECTS OF ULTRAVIOLET RADIATIONS | Bruschettini S.r.l. (IT) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009059748-A2 | COMPOSITIONS FOR THE TOPICAL PROTECTION OF THE OCULAR TISSUES FROM THE DAMAGING EFFECTS OF ULTRAVIOLET RADIATIONS | BRUSCHETTINI S.R.L. (IT) | 2009-05-14 | — | — | WO | disclosed |
| EP-2057983-A1 | Compositions for the topical protection of the ocular tissues from the damaging effects of ultraviolet radiations | Bruschettini S.r.l. (IT) | 2009-05-13 | — | — | EP | disclosed |