Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935010 | 0.89 | MEN1 (0.38) | NPSR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL5702186 | 0.88 | NPSR1 (0.35) | NPSR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL14755443 | 0.88 | MAPT (0.43) | NPSR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL10225867 | 0.84 | MEN1 (0.39) | NPSR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL14742524 | 0.82 | ALOX12 (0.35) | NPSR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL10517540 | 0.82 | MEN1 (0.44) | NPSR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL5786389 | 0.81 | HTT (0.42) | NPSR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL9952911 | 0.80 | CYP3A4 (0.35) | NPSR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL5610706 | 0.80 | ALDH1A1 (0.43) | HTTMEN1KMT2ACYP3A4HPGD | |
| SCHEMBL20270701 | 0.79 | IMPDH2 (0.35) | NPSR1HTTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188728-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | Chromocell Corporation (US) | 2017-07-12 | — | — | EP | disclosed |
| WO-2016036980-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | CHROMOCELL CORPORATION (US) | 2016-03-10 | — | — | WO | disclosed |
| EP-2209790-A2 | EQUILIBRATIVE NUCLEOSIDE TRANSPORTER ENT1 INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009062990-A2 | EQUILIBRATIVE NUCLEOSIDE TRANSPORTER ENT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-05-22 | — | — | WO | disclosed |