SCHEMBL3657417

SCHEMBL3657417

O=C1OC(=O)Oc2c(cc3oc(=O)oc(=O)oc4cccc3c24)O1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 8/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
GLA P06280 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
PGAM1 P18669 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
EGFR P00533 1/20 0.33
NPC1 O15118 3/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GAA P10253 2/20 0.31
TTR P02766 4/20 0.31
RAB9A P51151 2/20 0.31
MGAM O43451 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267811 0.81 MAPT (0.31) MAOAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8761057 0.75 MAOA (0.40) MAOAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8026253 0.69 TYMS (0.35) MEN1KMT2A
SCHEMBL16612995 0.69 MAOA (0.46) MAOAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL3792305 0.68 MEN1 (0.30) MEN1KMT2A
SCHEMBL8745405 0.68 MAOA (0.30) MAOAEGFR
SCHEMBL8018963 0.68 MAOA (0.46) MAOAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL15512504 0.66 ALDH1A1 (0.34) MAOAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL620521 0.66 CYP2A6 (0.33) KDM4EALDH1A1HPGDHSD17B10CYP3A4
SCHEMBL9351775 0.66 MAPK1 (0.43) MAOAKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2235112-A2 SYNTHESIS OF DYES IN MIXING UNITS BASF SE (DE) 2010-10-06 EP disclosed
WO-2009074504-A2 SYNTHESIS OF DYES IN MIXING UNITS BASF SE (DE) 2009-06-18 WO disclosed