Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062205 | 0.76 | TSHR (0.35) | S1PR4TSHR | |
| SCHEMBL3068194 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL7661242 | 0.71 | KCNH2 (0.44) | TSHR | |
| SCHEMBL22242022 | 0.68 | KCNH2 (0.41) | S1PR4TSHR | |
| SCHEMBL13518972 | 0.66 | NNMT (0.44) | — | |
| SCHEMBL25646251 | 0.66 | SYK (0.42) | TSHR | |
| SCHEMBL30107989 | 0.65 | HTR7 (0.38) | TSHR | |
| SCHEMBL28387454 | 0.65 | KCNH2 (0.38) | TSHR | |
| SCHEMBL23530219 | 0.64 | CCR1 (0.32) | TSHR | |
| SCHEMBL24347496 | 0.62 | ADORA2A (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215088-A2 | 4,4-DISUBSTITUTED PIPERDINES AS RENIN INHIBITORS | Novartis AG (CH) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009056617-A2 | 4,4-DISUBSTITUTED PIPERDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-05-07 | — | — | WO | disclosed |