Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068194 | 0.78 | TSHR (0.33) | TSHRS1PR3 | |
| SCHEMBL3657628 | 0.76 | S1PR4 (0.36) | TSHRS1PR4 | |
| SCHEMBL30107989 | 0.75 | HTR7 (0.38) | TSHRMBOAT4 | |
| SCHEMBL7661242 | 0.74 | KCNH2 (0.44) | TSHRS1PR3NPC1ALDH1A1RAB9A | |
| SCHEMBL15228340 | 0.72 | TSHR (0.44) | TSHRGRIN1GRIN2BCASRNPC1 | |
| SCHEMBL22242022 | 0.72 | KCNH2 (0.41) | TSHRNPC1ALDH1A1RAB9AS1PR4 | |
| SCHEMBL2147686 | 0.71 | GBA1 (0.40) | MBOAT4NPC1MAPTALDH1A1RAB9A | |
| SCHEMBL28387454 | 0.71 | KCNH2 (0.38) | TSHR | |
| SCHEMBL8030956 | 0.70 | CCR1 (0.48) | GRIN1GRIN2BMBOAT4NPC1ALDH1A1 | |
| SCHEMBL17885768 | 0.70 | RAB9A (0.34) | GRIN1GRIN2BMBOAT4NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267713-A1 | 4,4-DISUBSTITUTED PIPERIDINES | HEROLD PETER | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267713-A1 | 4,4-DISUBSTITUTED PIPERIDINES | REN, AGTR2, AVPR2 | TSHR 2279/4885GRIN1 832/4885GRIN2B 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.