SCHEMBL3658005

SCHEMBL3658005

CCOC(=O)c1ccc(-c2ccc(O)cc2)cc1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.61
CA1 P00915 5/20 0.61
CA2 P00918 5/20 0.61
CA7 P43166 5/20 0.61
CA9 Q16790 5/20 0.61
CA14 Q9ULX7 5/20 0.61
ESR1 P03372 2/20 0.59
ESR2 Q92731 2/20 0.59
HSD17B1 P14061 1/20 0.51
LMNA P02545 2/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 1/20 0.49
KMT2A Q03164 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TSHR P16473 1/20 0.49
PIM1 P11309 1/20 0.46
IRAK1 P51617 1/20 0.46
CAMK2B Q13554 1/20 0.46
CAMK2G Q13555 1/20 0.46
CAMK2D Q13557 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13140804 0.92 TSHR (0.57) CA12CA1CA2CA7CA9
SCHEMBL12991540 0.87 TSHR (0.58) CA12CA1CA2CA7CA9
SCHEMBL1656743 0.86 CA12 (0.74) CA12CA1CA2CA7CA9
SCHEMBL6710564 0.86 MAPK1 (0.52) CA12CA1CA2CA7CA9
SCHEMBL28688149 0.84 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL3994731 0.84 GAA (0.52) CA12CA2CA7CA9CA14
SCHEMBL28675075 0.83 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL28654350 0.82 HSD17B10 (0.50) CA12CA1CA2CA7CA9
SCHEMBL3624895 0.82 RXRA (0.54) CA12CA1CA2CA7CA9
SCHEMBL903983 0.81 ESR1 (0.89) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 CN claimed
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 CN disclosed
CN-113748021-A Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2021-12-03 CN disclosed
US-20110059942-A1 Azetidinyl G-Protein Coupled Receptor Agonists PROSIDION LIMITED (GB) 2011-03-10 US disclosed
EP-2215077-A1 AZETIDINYL G-PROTEIN COUPLED RECEPTOR AGONISTS Prosidion Limited (GB) 2010-08-11 EP disclosed
WO-2009050522-A1 AZETIDINYL G-PROTEIN COUPLED RECEPTOR AGONISTS PROSIDION LIMITED (GB) 2009-04-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059942-A1 Azetidinyl G-Protein Coupled Receptor Agonists GPR119, GIPR, GPR39 CA12 4803/4885CA1 4850/4885CA2 3914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.