SCHEMBL3658221

SCHEMBL3658221

CC1(C)[C@H](C=CC=O)[C@H]1C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10336836 1.00 UGT2B7 (0.32) UGT2B7LMNA
SCHEMBL3678270 1.00 UGT2B7 (0.32) UGT2B7LMNA
SCHEMBL11055234 1.00 UGT2B7 (0.32) UGT2B7LMNA
SCHEMBL11118246 0.82
SCHEMBL3649529 0.81 LMNA (0.30) LMNA
SCHEMBL9442649 0.81 LMNA (0.30) LMNA
SCHEMBL3658711 0.81 LMNA (0.30) LMNA
SCHEMBL3649532 0.81 LMNA (0.30) LMNA
SCHEMBL11241764 0.81 LMNA (0.30) LMNA
SCHEMBL3216533 0.79 LMNA (0.33) UGT2B7LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9247750-B2 Polyenylcyclopropanecarboxylic esters with high insecticidal activity ENDURA S.P.A. (IT) 2016-02-02 US disclosed
EP-2203064-B9 POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY ENDURA SPA (IT) 2014-11-19 EP disclosed
EP-2203064-B1 POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY ENDURA SPA (IT) 2013-02-13 EP disclosed
US-20100210721-A1 POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY ENDURA S.P.A. (IT) 2010-08-19 US disclosed
EP-2203064-A1 POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY Endura S.p.a. (IT) 2010-07-07 EP disclosed
WO-2009037228-A1 POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY ENDURA S.P.A. (IT) 2009-03-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210721-A1 POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY DDT, MCCC2, PCCA UGT2B7 3742/4885LMNA 1338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.