SCHEMBL3216533

SCHEMBL3216533

CC1(C)[C@H](C(=O)O)[C@@H]1C=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
APLNR P35414 1/20 0.32
UGT2B7 P16662 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515780 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL2692874 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL8037708 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL3247829 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL358648 1.00 LMNA (0.33) LMNAAPLNRUGT2B7KMT2A
SCHEMBL11136789 0.80 LMNA (0.37) LMNA
SCHEMBL7064292 0.80 LMNA (0.37) LMNA
SCHEMBL3678270 0.79 UGT2B7 (0.32) LMNAUGT2B7
SCHEMBL3658221 0.79 UGT2B7 (0.32) LMNAUGT2B7
SCHEMBL11055234 0.79 UGT2B7 (0.32) LMNAUGT2B7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274314-B1 PROCESS FOR THE PREPARATION OF PENTAFLUOROPHENYLMETHYL 2,2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLATE, AND ITS USE IN THE SYNTHESIS OF PESTICIDAL PRODUCTS ROUSSEL-UCLAF (FR) 1990-11-07 EP claimed
EP-0002849-B1 PROCESS FOR THE PREPARATION OF DI-(HALO)-VINYL COMPOUNDS AND DI-(HALO)-VINYL COMPOUNDS PRODUCED THEREBY SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-01-27 EP claimed
EP-0002849-A1 Process for the preparation of di-(halo)-vinyl compounds and di-(halo)-vinyl compounds produced thereby SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-07-11 EP claimed
EP-2114871-B1 A CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2014-07-30 EP disclosed
US-20100041750-A1 Ester Compound and Use Thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-18 US disclosed
EP-1018503-B1 Process of producing cyclopropanecarboxylate compounds SUMITOMO CHEMICAL CO (JP) 2003-08-13 EP disclosed
US-6414181-B1 REACTING CYCLOPROPANECARBALDEHYDE COMPOUND WITH DICARBOXYLATE COMPOUND IN PRESENCE OF AT LEAST ONE SECONDARY AMINE CHOOSEN FROM PIPERIDINE, MORPHOLINE, PYRROLIDINE, DIETHYLAMINE AND N-METHYLETHANOLAMINE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-07-02 US disclosed
EP-1209154-A1 Preparation of monofluoroalkenes Aventis CropScience GmbH (DE) 2002-05-29 EP disclosed
WO-2002040459-A1 PREPARATION OF MONOFLUOROALKENES BAYER CROPSCIENCE GMBH (DE) 2002-05-23 WO disclosed
EP-1018503-A1 Process of producing cyclopropanecarboxylate compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-07-12 EP disclosed
EP-0842137-B1 A PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR CHEMINOVA AGRO AS (DK) 2000-04-05 EP disclosed
EP-0133406-B1 CYCLOPROPANECARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION, THEIR USE AS PARASITICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1987-04-22 EP disclosed
US-4622337-A INSECTICIDES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-11-11 US disclosed
US-4513147-A Process for preparing cis-3-(2,2-dihalovinyl)-2,2-dimethylcyclopropanecarboxylic acid ROUSSEL UCLAF (FR) 1985-04-23 US disclosed
US-4464391-A Pesticides NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-08-07 US disclosed
US-4412069-A Process for preparing cyclopropane carboxylic acid derivatives ROUSSEL UCLAF (FR) 1983-10-25 US disclosed
US-4281182-A Novel lactones of cis 2,2-dimethyl-cyclopropane-1-carboxylic acid and their use ROUSSEL UCLAF (FR) 1981-07-28 US disclosed
US-4166063-A Lactones of 2,2-dimethyl-cyclopropane-1-carboxylic acids ROUSSEL UCLAF (FR) 1979-08-28 US disclosed
US-4156692-A Mixed anhydride of acetic acid and (1R,cis)-caronaldehydic acids SHELL OIL COMPANY (US) 1979-05-29 US disclosed
US-4132717-A Enol lactone intermediate for the preparation of (1R,cis)-caronaldehydic acid SHELL OIL COMPANY (US) 1979-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041750-A1 Ester Compound and Use Thereof CYP51A1, NOTUM, CYP46A1 LMNA 2762/4885APLNR 4344/4885UGT2B7 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.