Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786607 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2AHPGDMAPTADORA1 | |
| SCHEMBL3775573 | 0.76 | RORC (0.47) | SMN1; SMN2KMT2AMAPTMEN1USP30 | |
| SCHEMBL3784705 | 0.75 | ADORA1 (0.64) | SMN1; SMN2KMT2AMAPTADORA1ADORA2A | |
| SCHEMBL3658323 | 0.71 | TMIGD3 (0.58) | SMN1; SMN2KMT2AHPGDMAPTADORA1 | |
| SCHEMBL3779774 | 0.70 | RAB9A (0.46) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL4073631 | 0.68 | MEN1 (0.40) | SMN1; SMN2KMT2AADORA1ADORA2ATMIGD3 | |
| SCHEMBL3659566 | 0.67 | ALDH1A1 (0.54) | SMN1; SMN2KMT2AHPGDMAPTMEN1 | |
| SCHEMBL3658445 | 0.67 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AHPGDMAPTMEN1 | |
| SCHEMBL3656851 | 0.66 | ALDH1A1 (0.55) | SMN1; SMN2KMT2AHPGDMAPTMEN1 | |
| SCHEMBL3662329 | 0.65 | ROCK1 (0.50) | SMN1; SMN2KMT2AHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217565-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2010-08-18 | — | — | EP | claimed |
| WO-2009061652-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-14 | — | — | WO | claimed |