Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796973 | 0.85 | HPGD (0.44) | TSHRGPR139P2RX7NPC1RAB9A | |
| SCHEMBL36590 | 0.85 | TSHR (0.63) | TSHRP2RX7TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29566931 | 0.85 | TSHR (0.63) | TSHRP2RX7TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4477586 | 0.82 | F2 (0.59) | TSHRP2RX7NPC1RAB9AERCC5 | |
| SCHEMBL28352383 | 0.79 | TSHR (0.53) | TSHRGPR139P2RX7NPC1RAB9A | |
| SCHEMBL28767306 | 0.78 | MAPK1 (0.49) | TSHRGPR139TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL21676265 | 0.77 | TSHR (0.53) | TSHRP2RX7NPC1TAS1R3TAS1R1 | |
| Benzoyl Peroxide SCHEMBL2125046 | 0.74 | LMNA (0.68) | TSHRNPC1RAB9AALDH1A1POLB | |
| Benzoyl Peroxide SCHEMBL27992938 | 0.74 | LMNA (0.68) | TSHRNPC1RAB9AALDH1A1POLB | |
| SCHEMBL993113 | 0.74 | TSHR (0.59) | TSHRP2RX7TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162399-A1 | impact modifier composition comprises structural units derived from: at least one silicone rubber monomer, a branched acrylate rubber monomer | GENERAL ELECTRIC COMPANY | 2004-08-19 | — | — | US | disclosed |