Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | POLR1A | O95602 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365444 | 0.87 | ALDH1A1 (0.48) | ALDH1A1UTS2RTDP1CHRM1MEN1 | |
| SCHEMBL366166 | 0.86 | ALDH1A1 (0.43) | ALDH1A1UTS2RTDP1CHRM1MEN1 | |
| SCHEMBL366992 | 0.86 | ALDH1A1 (0.45) | ALDH1A1UTS2RTDP1CHRM1MEN1 | |
| SCHEMBL365945 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TDP1CHRM1MEN1KMT2A | |
| SCHEMBL366730 | 0.83 | NR4A2 (0.43) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL366312 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL366408 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL364887 | 0.82 | ALDH1A1 (0.52) | ALDH1A1UTS2RTDP1MEN1KMT2A | |
| SCHEMBL365839 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1CHRM1MEN1KMT2A | |
| SCHEMBL365801 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1MEN1KMT2ARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |