Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL349509 | 0.96 | RNPEP (0.40) | RNPEPALDH1A1L3MBTL1CYP2C9GAA | |
| Water SCHEMBL7531308 | 0.96 | RNPEP (0.40) | RNPEPALDH1A1L3MBTL1CYP2C9GAA | |
| SCHEMBL6777811 | 0.83 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1CYP2C9GAAHTT | |
| SCHEMBL6850448 | 0.83 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1CYP2C9GAAHTT | |
| Hydrochloric Acid SCHEMBL6777810 | 0.81 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CYP2C9GAAHTT | |
| Hydrochloric Acid SCHEMBL6777809 | 0.81 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CYP2C9GAAHTT | |
| SCHEMBL10519746 | 0.80 | PPID (0.49) | ALDH1A1L3MBTL1CYP2C9METAP2METAP1 | |
| SCHEMBL10519749 | 0.80 | PPID (0.49) | ALDH1A1L3MBTL1CYP2C9METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL9419887 | 0.79 | METAP2 (0.37) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL9421023 | 0.79 | L3MBTL1 (0.39) | RNPEPALDH1A1L3MBTL1CYP2C9METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209390-A1 | COMPLEX PRODUCT WITH ADVANCED ASSIMILATION EFFICACY FOR HUMANS AND ITS UTILIZATION | Ficsur, Tibor (HU) | 2010-07-28 | — | — | EP | claimed |
| WO-2009040590-A1 | COMPLEX PRODUCT WITH ADVANCED ASSIMILATION EFFICACY FOR HUMANS AND ITS UTILIZATION | FICSUR TIBOR (HU) | 2009-04-02 | — | — | WO | claimed |
| EP-2209390-A1 | COMPLEX PRODUCT WITH ADVANCED ASSIMILATION EFFICACY FOR HUMANS AND ITS UTILIZATION | Ficsur, Tibor (HU) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009040590-A1 | COMPLEX PRODUCT WITH ADVANCED ASSIMILATION EFFICACY FOR HUMANS AND ITS UTILIZATION | FICSUR TIBOR (HU) | 2009-04-02 | — | — | WO | disclosed |