SCHEMBL3661443

SCHEMBL3661443

CCCCc1ccc(OC)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 0.69
TUBB P07437 2/20 0.69
TUBA3C P0DPH7 2/20 0.69
TUBA1B P68363 2/20 0.69
TUBA4A P68366 2/20 0.69
TUBB4B P68371 2/20 0.69
TUBB3 Q13509 2/20 0.69
TUBB2A Q13885 2/20 0.69
TUBB8 Q3ZCM7 2/20 0.69
TUBA3E Q6PEY2 2/20 0.69
TUBA1A Q71U36 2/20 0.69
TUBA1C Q9BQE3 2/20 0.69
TUBB6 Q9BUF5 2/20 0.69
TUBB2B Q9BVA1 2/20 0.69
TUBB1 Q9H4B7 2/20 0.69
CYP3A4 P08684 2/20 0.67
CYP1A2 P05177 1/20 0.67
TSHR P16473 1/20 0.67
NFKB1 P19838 1/20 0.67
MEN1 O00255 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9708412 0.95 TUBB4A (0.71) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3662929 0.93 TUBB4A (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3658739 0.93 TUBB4A (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3659045 0.93 TUBB4A (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL6312374 0.93 TUBB4A (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29833121 0.89 CYP3A4 (0.71) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL901444 0.89 CYP3A4 (0.71) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL31710801 0.86 TAAR1 (0.69) CYP3A4CYP1A2TSHRLMNAMAPK1
SCHEMBL677607 0.86 TAAR1 (0.69) CYP3A4CYP1A2TSHRLMNAMAPK1
SCHEMBL15535668 0.86 TUBB4A (0.69) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4774229-A ANTITUMOR AGENTS, SKIN DISORDERS, CANCER TREATMENT CHEMEX PHARMACEUTICALS, INC. (US) 1988-09-27 US claimed
CN-118209604-A Preparation method and application of electrochemical sensor based on chitosan/polyacrylamide/iron phthalocyanine hydrogel 扬州大学 2024-06-18 CN disclosed
CN-114190501-B Method for preparing Lepista sordida mycelium beverage 达州市农业科学研究院 2024-01-16 CN disclosed
CN-116023313-A Docalcitol compound crystal and capsule thereof 南京海鲸药业股份有限公司 2023-04-28 CN disclosed
CN-114190501-A Preparation method of Lepista sordida mycelium beverage 达州市农业科学研究院 2022-03-18 CN disclosed
US-9364424-B2 Topical cosmetic skin lightening compositions and methods of use thereof STIEFEL LABORATORIES, INC. (US) 2016-06-14 US disclosed
US-20160074315-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. 2016-03-17 US disclosed
EP-2219600-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. (US) 2010-08-25 EP disclosed
WO-2009067095-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. (US) 2009-05-28 WO disclosed
EP-1602354-B1 Use of polyglutamic acid or its salts MEIJI SEIKA KAISHA (JP) 2008-11-05 EP disclosed
EP-1604647-B1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof CHISSO CORP (JP) 2008-05-07 EP disclosed
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair MEIJI SEIKA KAISHA, LTD. (JP) 2006-07-27 US disclosed
US-20060018867-A1 Cosmetic composition and production thereof ICHIMARU PHARCOS CO., LTD 2006-01-26 US disclosed
EP-1604647-A1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof Ichimaru Pharcos Co., Ltd. (JP) 2005-12-14 EP disclosed
EP-1602354-A1 HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR Meiji Seika Kaisha, Ltd. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair CUTA, COL14A1, PRKDC TUBB4A 2106/4885TUBB 1148/4885TUBA3C 1954/4885
US-20060018867-A1 Cosmetic composition and production thereof CUTA, PARG, TYR TUBB4A 1242/4885TUBB 614/4885TUBA3C 1888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.