Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.71 |
| ▸ | TUBB | P07437 | 2/20 | 0.71 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.71 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.71 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.71 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.71 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.71 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.71 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.71 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.71 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.71 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.71 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.71 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.71 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658739 | 0.98 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3662929 | 0.98 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3659045 | 0.98 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6312374 | 0.98 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3661443 | 0.95 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29833121 | 0.87 | CYP3A4 (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL901444 | 0.87 | CYP3A4 (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6566912 | 0.86 | HTR1A (0.69) | CYP3A4CYP1A2TSHRLMNA | |
| SCHEMBL9485313 | 0.85 | HTR1A (0.72) | CYP3A4CYP1A2TSHRLMNA | |
| SCHEMBL7246840 | 0.85 | HTR1A (0.72) | CYP3A4CYP1A2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016486-A1 | SUBSTITUTED DIPHENYLETHYLENES AND ANALOGUES OR DERIVATIVES THEREOF | ASTON MOLECULES LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |