Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.53 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5407042 | 0.79 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5407003 | 0.78 | ALDH1A1 (0.74) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1199874 | 0.73 | KIF11 (0.46) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL10592441 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL20721585 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4194552 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL3537019 | 0.73 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2083483 | 0.71 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL27587625 | 0.70 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL24797472 | 0.69 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227464-A1 | DERIVATIVES OF 1-[(IMIDAZOLIDIN-2-YL)IMINO)]INDAZOLE | Imperial Innovations Limited (GB) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009071906-A1 | DERIVATIVES OF 1-[(IMIDAZOLIDIN-2-YL)IMINO)]INDAZOLE | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-06-11 | — | — | WO | disclosed |