SCHEMBL3661499

SCHEMBL3661499

CC#CCCCCCOc1cccc(NC)c1F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.34
SLC6A4 P31645 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
PTPN1 P18031 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HRH1 P35367 1/20 0.32
APP P05067 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2C9 P11712 2/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
HTR1B P28222 2/20 0.31
ALDH1A1 P00352 3/20 0.30
LMNA P02545 1/20 0.30
MEN1 O00255 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3660239 0.99 L3MBTL1 (0.35) L3MBTL1SLC6A4TDP1PTPN1NPC1
SCHEMBL3664404 0.94 SMN1; SMN2 (0.34) L3MBTL1SLC6A4TDP1PTPN1NPC1
SCHEMBL3659956 0.90 APP (0.33) L3MBTL1SLC6A4TDP1HRH1APP
SCHEMBL3659801 0.86 L3MBTL1 (0.37) L3MBTL1SLC6A4TDP1PTPN1HRH1
SCHEMBL3664516 0.85 EGFR (0.35) L3MBTL1SLC6A4TDP1PTPN1KDM4E
SCHEMBL3659751 0.85 EGFR (0.35) L3MBTL1SLC6A4TDP1PTPN1KDM4E
SCHEMBL3662259 0.83 L3MBTL1 (0.36) L3MBTL1SLC6A4TDP1PTPN1HRH1
SCHEMBL3664058 0.82 L3MBTL1 (0.35) L3MBTL1SLC6A4TDP1PTPN1NPC1
SCHEMBL3662361 0.82 L3MBTL1 (0.35) L3MBTL1SLC6A4TDP1PTPN1HRH1
SCHEMBL3662868 0.81 APP (0.35) L3MBTL1RAB9AAPPALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 L3MBTL1 40/4885SLC6A4 3430/4885TDP1 4310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.