SCHEMBL3664058

SCHEMBL3664058

CCCC#CCCCOc1cccc(NC)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
PTPN1 P18031 1/20 0.34
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2C9 P11712 1/20 0.33
SLC6A4 P31645 2/20 0.33
HRH1 P35367 1/20 0.33
APP P05067 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MEN1 O00255 1/20 0.32
HTR1B P28222 2/20 0.31
CYP2D6 P10635 1/20 0.31
PTGS2 P35354 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3661720 0.93 PTPN1 (0.33) L3MBTL1PPARGPPARAPTPN1KMT2A
SCHEMBL3662361 0.92 L3MBTL1 (0.35) L3MBTL1PPARGPPARAPTPN1KMT2A
SCHEMBL3658303 0.90 PPARG (0.36) L3MBTL1PPARGPPARAPTPN1KMT2A
SCHEMBL3659801 0.88 L3MBTL1 (0.37) L3MBTL1PPARGPPARAPTPN1KMT2A
SCHEMBL3656907 0.87 PTGS2 (0.34) L3MBTL1KMT2AAPPRAB9APTGS2
SCHEMBL3664404 0.87 SMN1; SMN2 (0.34) L3MBTL1PTPN1SLC6A4HRH1APP
SCHEMBL3663858 0.85 PTGS2 (0.36) L3MBTL1PPARGPPARAPTPN1KMT2A
SCHEMBL3662391 0.84 APP (0.33) L3MBTL1PTPN1CYP1A2CYP2C19SLC6A4
SCHEMBL3662973 0.84 PTGS2 (0.38) PPARGPPARAPTPN1APPPTGS2
SCHEMBL3660239 0.83 L3MBTL1 (0.35) L3MBTL1PPARGPPARAPTPN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 L3MBTL1 40/4885PPARG 1061/4885PPARA 1791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.