SCHEMBL3662868

SCHEMBL3662868

CC#CCOc1cccc(NC)c1F

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.35
HTR1A P08908 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.31
KMT2A Q03164 1/20 0.31
PDE4B Q07343 1/20 0.30
MMP2 P08253 3/20 0.30
ADAM17 P78536 3/20 0.30
MMP7 P09237 2/20 0.30
MMP8 P22894 2/20 0.30
MMP13 P45452 2/20 0.30
MMP1 P03956 2/20 0.30
MMP9 P14780 2/20 0.30
MMP12 P39900 1/20 0.30
RAB9A P51151 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3656186 0.86 APP (0.34) APPL3MBTL1KMT2ARAB9AALDH1A1
SCHEMBL3659956 0.85 APP (0.33) APPL3MBTL1
SCHEMBL3656907 0.84 PTGS2 (0.34) APPHTR1AL3MBTL1KMT2ARAB9A
SCHEMBL3664404 0.84 SMN1; SMN2 (0.34) APPL3MBTL1RAB9A
SCHEMBL3662005 0.83 MAPT (0.41) APPHTR1A
SCHEMBL3660239 0.82 L3MBTL1 (0.35) APPHTR1AL3MBTL1RAB9A
SCHEMBL3663858 0.81 PTGS2 (0.36) APPL3MBTL1KMT2AALDH1A1PTGS2
SCHEMBL3661499 0.81 L3MBTL1 (0.34) APPHTR1AL3MBTL1KMT2ARAB9A
SCHEMBL3662973 0.80 PTGS2 (0.38) APPPTGS2
SCHEMBL3758606 0.76 RPS6KA1 (0.36) HTR1AL3MBTL1PDE4BMMP2ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 APP 2380/4885HTR1A 2686/4885L3MBTL1 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.