Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL403378 | 0.90 | CYP1A2 (0.40) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL7787482 | 0.78 | GABRA1 (0.44) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL196777 | 0.76 | HSP90AA1 (0.46) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL12798321 | 0.76 | S100A4 (0.46) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL29590656 | 0.76 | HSP90AA1 (0.46) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL8365116 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 | |
| Acetic Acid SCHEMBL404308 | 0.74 | PRNP (0.40) | SMN1; SMN2LMNAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL16958593 | 0.73 | GABRA1 (0.39) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL43286 | 0.73 | GABRA1 (0.44) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL3661598 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDTSHRLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222657-B1 | PYRANDIONES, THIOPYRANDIONES AND CYCLOHEXANTRIONES HAVING HERBICIDAL PROPERTIES | SYNGENTA LTD (GB) | 2012-09-12 | — | — | EP | disclosed |
| EP-2222657-A1 | 4-PHENYLPYRANE-3,5-DIONES, 4-PHENYLTHIOPYRANE-3,5-DIONES AND 2-PHENYLCYCLOHEXANE-1,3,5-TRIONES AS HERBICIDES | Syngenta Limited (GB) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009074314-A1 | 4-PHENYLPYRANE-3,5-DIONES, 4-PHENYLTHIOPYRANE-3,5-DIONES AND 2-PHENYLCYCLOHEXANE-1,3,5-TRIONES AS HERBICIDES | SYNGENTA LIMITED (GB) | 2009-06-18 | — | — | WO | disclosed |