SCHEMBL196777

SCHEMBL196777

CCc1cc(Br)ccc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.46
TLR9 Q9NR96 1/20 0.46
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
S100A4 P26447 1/20 0.41
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
ALOX15 P16050 1/20 0.37
MAPK1 P28482 2/20 0.36
PRNP P04156 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29590656 1.00 HSP90AA1 (0.46) HSP90AA1TLR9GABRA1GABRB2SMN1; SMN2
SCHEMBL7787482 0.82 GABRA1 (0.44) HSP90AA1TLR9GABRA1GABRB2SMN1; SMN2
SCHEMBL26667643 0.81 HSP90AA1 (0.38) HSP90AA1TLR9SMN1; SMN2L3MBTL1LMNA
SCHEMBL882732 0.80 PYCR1 (0.47) HSP90AA1TLR9GABRA1GABRB2SMN1; SMN2
SCHEMBL12798321 0.80 S100A4 (0.46) HSP90AA1TLR9GABRA1GABRB2SMN1; SMN2
SCHEMBL1047304 0.80 HSP90AA1 (0.46) HSP90AA1TLR9SMN1; SMN2L3MBTL1LMNA
SCHEMBL28808700 0.79 HSP90AA1 (0.44) HSP90AA1TLR9L3MBTL1TSHRS100A4
SCHEMBL11797035 0.78 TRPA1 (0.43) GABRA1GABRB2SMN1; SMN2L3MBTL1LMNA
SCHEMBL4882598 0.78 GABRA1 (0.41) GABRA1GABRB2SMN1; SMN2L3MBTL1LMNA
SCHEMBL8365116 0.78 SMN1; SMN2 (0.41) GABRA1GABRB2SMN1; SMN2L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250374741-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORP (JP) 2025-12-04 US disclosed
EP-4479479-B1 SILPHENYLENE POLYMERS WACKER CHEMIE AG (DE) 2025-08-13 EP disclosed
US-20250215260-A1 SILPHENYLENE POLYMERS WACKER CHEMIE AG (DE) 2025-07-03 US disclosed
EP-4479479-A1 SILPHENYLENE POLYMERS Wacker Chemie AG (DE) 2024-12-25 EP disclosed
WO-2024185812-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND 富士フイルム株式会社 2024-09-12 WO disclosed
US-11858880-B2 Anti-fungals compounds targeting the synthesis of fungal sphingolipids THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-01-02 US disclosed
WO-2023222203-A1 SILPHENYLENE POLYMERS WACKER CHEMIE AG (DE) 2023-11-23 WO disclosed
US-20230295139-A1 SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS UNIVERSITY OF KWAZULU-NATAL (ZA) 2023-09-21 US disclosed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
EP-0023314-B1 PROCESS FOR PREPARING POLY(ARYLENE SULFIDES) BAYER AG (DE) 1983-07-20 EP disclosed
EP-0075769-A1 Process for producing poly-arylene sulfides BAYER AG (DE) 1983-04-06 EP disclosed
US-4362864-A Process for the preparation of polyarylene sulphides BAYER AKTIENGESELLSCHAFT (DE) 1982-12-07 US disclosed
EP-0065689-A1 Method of producing poly(arylene sulfides) BAYER AG (DE) 1982-12-01 EP disclosed
US-4331801-A Process for the preparation of polyarylene sulphides BAYER AKTIENGESELLSCHAFT (DE) 1982-05-25 US disclosed
EP-0040747-A2 Process for preparing polyarylene sulfides BAYER AG (DE) 1981-12-02 EP disclosed
US-4303781-A Process for the preparation of polyarylene sulphides BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed
EP-0023314-A1 Process for preparing poly(arylene sulfides) BAYER AG (DE) 1981-02-04 EP disclosed
EP-0023313-A1 Process for preparing poly(arylene sulfides) BAYER AG (DE) 1981-02-04 EP disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11858880-B2 Anti-fungals compounds targeting the synthesis of fungal sphingolipids ERG28, UGCG, DPM1 HSP90AA1 3181/4885TLR9 4209/4885GABRA1 4267/4885
US-20230295139-A1 SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS NAAA, CNR2, AADAC HSP90AA1 2107/4885TLR9 3297/4885GABRA1 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.