Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966029 | 0.80 | CYP2C19 (0.54) | TMEM97KCNH2MEN1KMT2A | |
| SCHEMBL9781250 | 0.79 | ALDH1A1 (0.69) | ALDH1A1TMEM97KCNH2MEN1KMT2A | |
| SCHEMBL3966026 | 0.78 | SIGMAR1 (0.53) | ALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL3099211 | 0.78 | SIGMAR1 (0.53) | ALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL6354279 | 0.75 | ALDH1A1 (0.63) | ALDH1A1TMEM97KCNH2MEN1KMT2A | |
| SCHEMBL18893310 | 0.75 | ALDH1A1 (0.73) | ALDH1A1TMEM97KCNH2MEN1KMT2A | |
| SCHEMBL6235327 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TMEM97KCNH2MEN1KMT2A | |
| SCHEMBL12954738 | 0.73 | ALDH1A1 (0.71) | ALDH1A1TMEM97KCNH2MEN1KMT2A | |
| SCHEMBL14731813 | 0.72 | TMEM97 (0.86) | ALDH1A1TMEM97KCNH2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5967318 | 0.72 | ALDH1A1 (0.55) | ALDH1A1TMEM97KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215077-A1 | AZETIDINYL G-PROTEIN COUPLED RECEPTOR AGONISTS | Prosidion Limited (GB) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009050522-A1 | AZETIDINYL G-PROTEIN COUPLED RECEPTOR AGONISTS | PROSIDION LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |