Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966026 | 0.83 | SIGMAR1 (0.53) | CYP2C19CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL3099211 | 0.83 | SIGMAR1 (0.53) | CYP2C19CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL9415891 | 0.82 | CYP2C19 (0.63) | CYP2C19CYP1A2CYP2D6KCNH2TMEM97 | |
| Hydrochloric Acid SCHEMBL11352044 | 0.81 | CYP2C19 (0.66) | CYP2C19CYP1A2CYP2D6KCNH2TMEM97 | |
| SCHEMBL3661622 | 0.80 | ALDH1A1 (0.58) | KCNH2TMEM97MEN1KMT2A | |
| SCHEMBL7855536 | 0.78 | CYP2C19 (0.53) | CYP2C19CYP1A2CYP2D6KCNH2TMEM97 | |
| SCHEMBL2257390 | 0.76 | KCNH2 (0.56) | CYP2C19CYP1A2CYP2D6KCNH2TMEM97 | |
| SCHEMBL2257396 | 0.76 | KCNH2 (0.56) | CYP2C19CYP1A2CYP2D6KCNH2TMEM97 | |
| SCHEMBL19685408 | 0.75 | CYP2C19 (0.58) | CYP2C19CYP1A2CYP2D6KCNH2TMEM97 | |
| SCHEMBL3961688 | 0.74 | MEN1 (0.57) | MEN1KMT2APOLBMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784407-A4 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2009-02-11 | — | — | EP | disclosed |
| EP-1784407-A1 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025634-A1 | 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |