Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662398 | 0.96 | PPARG (0.67) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| SCHEMBL3658659 | 0.95 | PPARG (0.65) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| SCHEMBL3660458 | 0.95 | PPARG (0.65) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| SCHEMBL3659531 | 0.95 | PPARG (0.65) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| SCHEMBL18397790 | 0.81 | PPARG (0.65) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| SCHEMBL18397897 | 0.81 | PPARG (0.65) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| SCHEMBL11510798 | 0.81 | PPARG (0.65) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| SCHEMBL12325511 | 0.81 | PPARG (0.65) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| Hydrochloric Acid SCHEMBL18397798 | 0.80 | LOXL2 (0.64) | PPARGCYP11B1MAOBCYP11B2KDM4E | |
| SCHEMBL3661429 | 0.80 | ALOX15 (0.72) | PPARGMAOBKDM4EALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11642288-B2 | Skin external composition | KAO CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| CN-111491604-B | Method for producing composition containing hardly water-soluble aromatic compound | 花王株式会社 | 2023-03-21 | — | — | CN | disclosed |
| EP-4104862-A1 | SKIN COMPOSITION FOR EXTERNAL USE | Kao Corporation (JP) | 2022-12-21 | — | — | EP | disclosed |
| EP-3733155-B1 | METHOD FOR MANUFACTURING COMPOSITION THAT INCLUDES POORLY WATER-SOLUBLE AROMATIC COMPOUND | KAO CORP (JP) | 2022-11-23 | — | — | EP | disclosed |
| US-20220287923-A1 | SKIN EXTERNAL COMPOSITION | KAO CORPORATION (JP) | 2022-09-15 | — | — | US | disclosed |
| US-11419797-B2 | Method for producing composition containing hardly water-soluble aromatic compound | KAO CORPORATION (JP) | 2022-08-23 | — | — | US | disclosed |
| EP-4032524-A1 | METHOD FOR PRODUCING COMPOSITION CONTAINING HARDLY WATER-SOLUBLE AROMATIC COMPOUND | Kao Corporation (JP) | 2022-07-27 | — | — | EP | disclosed |
| CN-113950336-A | Composition for external application to skin | 花王株式会社 | 2022-01-18 | — | — | CN | disclosed |
| US-20210059909-A1 | METHOD FOR PRODUCING COMPOSITION CONTAINING HARDLY WATER-SOLUBLE AROMATIC COMPOUND | KAO CORPORATION (JP) | 2021-03-04 | — | — | US | disclosed |
| EP-3733155-A1 | METHOD FOR MANUFACTURING COMPOSITION THAT INCLUDES POORLY WATER-SOLUBLE AROMATIC COMPOUND | Kao Corporation (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9364424-B2 | Topical cosmetic skin lightening compositions and methods of use thereof | STIEFEL LABORATORIES, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160074315-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. | 2016-03-17 | — | — | US | disclosed |
| EP-2219600-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009067095-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2009-05-28 | — | — | WO | disclosed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060018867-A1 | Cosmetic composition and production thereof | ICHIMARU PHARCOS CO., LTD | 2006-01-26 | — | — | US | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1602354-A1 | HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR | Meiji Seika Kaisha, Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | PPARG 1178/4885CYP11B1 4654/4885MAOB 3870/4885 |
| US-20060018867-A1 | Cosmetic composition and production thereof | CUTA, PARG, TYR | PPARG 1824/4885CYP11B1 4279/4885MAOB 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.