Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 15/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 15/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375241 | 0.87 | ADRA2A (0.55) | ADRA2BADRA2CADRA2AHTR1ASLC6A4 | |
| SCHEMBL3961615 | 0.83 | NISCH (0.52) | ADRA2BADRA2CADRA2AHTR1ASLC6A4 | |
| SCHEMBL3665555 | 0.82 | ADRA2B (0.56) | ADRA2BADRA2CADRA2AHTR1ASLC6A4 | |
| SCHEMBL11370259 | 0.81 | ADRA2A (0.54) | ADRA2BADRA2CADRA2AHTR1ASLC6A4 | |
| SCHEMBL3667267 | 0.81 | ADRA2A (0.46) | ADRA2BADRA2CADRA2AHTR1ASLC6A4 | |
| SCHEMBL3058505 | 0.78 | ADRA2A (0.53) | ADRA2BADRA2CADRA2AHTR1ASLC6A4 | |
| SCHEMBL11369733 | 0.78 | ADRA2A (0.53) | ADRA2BADRA2CADRA2AHTR1ASLC6A4 | |
| SCHEMBL11224297 | 0.76 | NISCH (0.54) | ADRA2BADRA2CADRA2AHTR1ANISCH | |
| Hydrochloric Acid SCHEMBL9654753 | 0.75 | NISCH (0.53) | ADRA2BADRA2CADRA2AHTR1ANISCH | |
| SCHEMBL3961636 | 0.74 | NISCH (0.50) | ADRA2BADRA2CADRA2AHTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455663-B2 | Halosubstituted aryloxyalkylimidazolines for use as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455663-B2 | Halosubstituted aryloxyalkylimidazolines for use as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455663-B2 | Halosubstituted aryloxyalkylimidazolines for use as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-20100280088-A1 | HALOSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280088-A1 | HALOSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280088-A1 | HALOSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2190823-A1 | HALOSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | Syngenta Participations AG (CH) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009036909-A1 | HALOSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009036909-A1 | HALOSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280088-A1 | HALOSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | GLRA3, GLRX3, GLRA1 | ADRA2B 299/4885ADRA2C 202/4885ADRA2A 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.