Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890312 | 0.81 | HIF1A (0.51) | HIF1AKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL2890313 | 0.81 | HIF1A (0.51) | HIF1AKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8371507 | 0.81 | HIF1A (0.67) | HIF1AKDM4EALDH1A1MAPTHTT | |
| SCHEMBL6460031 | 0.81 | HIF1A (0.67) | HIF1AKDM4EALDH1A1MAPTHTT | |
| SCHEMBL6460025 | 0.81 | HIF1A (0.67) | HIF1AKDM4EALDH1A1MAPTHTT | |
| SCHEMBL7588409 | 0.80 | HIF1A (0.43) | HIF1AKDM4EKMT2AMEN1TDP1 | |
| SCHEMBL23971953 | 0.78 | HIF1A (0.47) | HIF1AKMT2AALDH1A1RXFP1HDAC3 | |
| SCHEMBL123529 | 0.78 | HIF1A (0.52) | HIF1AKMT2AMEN1RXFP1 | |
| SCHEMBL828172 | 0.78 | HIF1A (0.52) | HIF1AKMT2AMEN1RXFP1 | |
| SCHEMBL483559 | 0.78 | HIF1A (0.52) | HIF1AKMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263463-A1 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |