Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123529 | 1.00 | HIF1A (0.52) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL30354029 | 1.00 | HIF1A (0.52) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL123530 | 1.00 | HIF1A (0.52) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL29765420 | 1.00 | HIF1A (0.52) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL14141835 | 1.00 | HIF1A (0.52) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL483559 | 1.00 | HIF1A (0.52) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL30158137 | 0.92 | MEN1 (0.45) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL13278820 | 0.92 | MEN1 (0.45) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL168688 | 0.92 | MEN1 (0.45) | HIF1AMEN1KMT2AGAAPPARG | |
| SCHEMBL168689 | 0.92 | MEN1 (0.45) | HIF1AMEN1KMT2AGAAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143275-B2 | Use of triazolopyrimidine derivatives as microbicides | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-27 | — | — | US | disclosed |
| US-20110098279-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES | LANXESS DEUTSCHLAND GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| US-7888371-B2 | For protecting engineered wood, timber, or plastic from phytopathogenic fungi | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-15 | — | — | US | disclosed |
| EP-1395117-B2 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES IN THE PROTECTION OF MATERIALS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-09-30 | — | — | EP | disclosed |
| US-7084137-B2 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-01 | — | — | US | disclosed |
| EP-1395117-B1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES IN THE PROTECTION OF MATERIALS | LANXESS DEUTSCHLAND GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-6835842-B2 | Microbiocides; bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | disclosed |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-14 | — | — | US | disclosed |
| EP-1395117-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES IN THE PROTECTION OF MATERIALS | Bayer Chemicals AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| US-20030207929-A1 | 3-nitroisoxazoles and their use in the protection of materials | LANXESS DEUTSCHLAND GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| EP-1173428-A1 | O-ARYL DITHIAZOLE DIOXIDES | Bayer Aktiengesellschaft (DE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2001046163-A2 | 3-NITRO-DIHYDRO-ISOXAZOLES AND OXAZINES AND THEIR USE AS MICROBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-28 | — | — | WO | disclosed |
| WO-2000064881-A1 | O-ARYL DITHIAZOLE DIOXIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-02 | — | — | WO | disclosed |
| US-6075019-A | Arylthio-dithiazindioxides and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| EP-0975611-A1 | 3-ALKOXY ISOTHIAZOLES | BAYER AG (DE) | 2000-02-02 | — | — | EP | disclosed |
| EP-0950055-A1 | ARYLTHIO-DITHIAZINDIOXIDES AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998045258-A1 | 1-CYANO-2-ALKYLTHIO-2-ARYLTHIOETHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998042689-A1 | 3-ALKOXY ISOTHIAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998039969-A1 | ALGICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |
| WO-1998029400-A1 | ARYLTHIO-DITHIAZINDIOXIDES AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | POT1, NAT1, GPX1 | HIF1A 2331/4885MEN1 97/4885KMT2A 4152/4885 |
| US-20110098279-A1 | USE OF TRIAZOLOPYRIMIDINE DERIVATIVES AS MICROBICIDES | ARG2, MSR1, TK2 | HIF1A 1989/4885MEN1 2916/4885KMT2A 3734/4885 |
| US-20030207929-A1 | 3-nitroisoxazoles and their use in the protection of materials | GPX1, NOX1, XDH | HIF1A 541/4885MEN1 1505/4885KMT2A 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.