Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662282 | 0.92 | HDAC6 (0.53) | HDAC6KMT2AMEN1POLBPKM | |
| SCHEMBL3662076 | 0.87 | KMT2A (0.55) | HDAC6KMT2AMEN1POLBPKM | |
| SCHEMBL4116588 | 0.85 | MEN1 (0.55) | KMT2AMEN1POLB | |
| SCHEMBL3656307 | 0.84 | HDAC6 (0.53) | HDAC6KMT2AMEN1POLBPKM | |
| SCHEMBL4121157 | 0.83 | KMT2A (0.55) | HDAC6KMT2AMEN1USP2CRHBP | |
| SCHEMBL3659352 | 0.79 | MEN1 (0.56) | KMT2AMEN1POLB | |
| SCHEMBL3659938 | 0.78 | KMT2A (0.61) | KMT2AMEN1POLBPKMUSP2 | |
| SCHEMBL3660498 | 0.78 | KMT2A (0.61) | KMT2AMEN1POLBPKMUSP2 | |
| SCHEMBL3660710 | 0.77 | KMT2A (0.66) | KMT2AMEN1POLBPKMUSP2 | |
| SCHEMBL3663347 | 0.77 | KMT2A (0.58) | HDAC6KMT2AMEN1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101827840-A | Imidazolidine-2,4-dione (hydantoin) derivatives useful as npy y2 receptor modulators | NOVARTIS AG | 2010-09-08 | — | — | CN | claimed |
| EP-2212314-A1 | IMIDAZOLIDINE-2,4-DIONE (HYDANTOIN) DERIVATIVES USEFUL AS NPY Y2 RECEPTOR MODULATORS | Novartis AG (CH) | 2010-08-04 | — | — | EP | claimed |
| WO-2009050200-A1 | IMIDAZOLIDINE-2,4-DIONE (HYDANTOIN) DERIVATIVES USEFUL AS NPY Y2 RECEPTOR MODULATORS | NOVARTIS AG (CH) | 2009-04-23 | — | — | WO | claimed |
| US-20090099243-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | claimed |
| CN-101827840-A | Imidazolidine-2,4-dione (hydantoin) derivatives useful as npy y2 receptor modulators | NOVARTIS AG | 2010-09-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099243-A1 | ORGANIC COMPOUNDS | SLCO4C1, SLCO1B1, SLCO1B3 | HDAC6 715/4885KMT2A 2020/4885MEN1 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.