Orotic Acid

Orotic Acid

SCHEMBL366203

O=C(O)c1cc(=O)[nH]c(=O)[nH]1.[KH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.95
▸ LMNA P02545 1/20 0.95
▸ CYP2C19 P33261 2/20 0.61
▸ CYP1A2 P05177 2/20 0.57
▸ ALOX15 P16050 1/20 0.54
▸ NFKB1 P19838 1/20 0.54
▸ BLM P54132 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ TSHR P16473 2/20 0.47
▸ GPR84 Q9NQS5 4/20 0.45
▸ GPR35 Q9HC97 3/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ GRIN2D O15399 1/20 0.44
▸ GRIN3B O60391 1/20 0.44
▸ GLA P06280 1/20 0.44
▸ GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orotic Acid SCHEMBL29394966 0.98 ALDH1A1 (1.00) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL20865 0.98 ALDH1A1 (1.00) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL431534 0.98 ALDH1A1 (1.00) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL16194627 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL1852415 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL23859825 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL672145 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL9726379 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL16916880 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL161885 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367169-A1 FORMULATIONS FOR PERSONALIZED METHODS OF TREATMENT FAETH THERAPEUTICS INC (US) 2025-12-04 — — US claimed
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 — — EP claimed
US-12220402-B2 Formulations for personalized methods of treatment FAETH THERAPEUTICS, INC. (US) 2025-02-11 — — US claimed
WO-2024130044-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) LUMINOUS MIND INC. (US) 2024-06-20 — — WO claimed
EP-4319788-A1 REGULATION OF CELLS AND ORGANISMS Tets, Victor (US) 2024-02-14 — — EP claimed
CN-116075238-A Formulations for personalized therapeutic methods 菲思治疗公司 2023-05-05 — — CN claimed
EP-4161501-A1 FORMULATIONS FOR PERSONALIZED METHODS OF TREATMENT Faeth Therapeutics, Inc. (US) 2023-04-12 — — EP claimed
WO-2022214966-A1 REGULATION OF CELLS AND ORGANISMS TETS VICTOR (US) 2022-10-13 — — WO claimed
EP-3212191-B1 TREATMENT FOR DEPRESSION AND DEPRESSIVE DISORDERS MEDLAB IP PTY LTD (AU) 2022-10-05 — — EP claimed
US-20220152093-A1 OPTIMIZED NUTRIENT SALT COMPOSITION VADAKKEMURI JOLLY MATHEW (IN) 2022-05-19 — — US claimed
US-20170312232-A1 TREATMENT FOR DEPRESSION AND DEPRESSIVE DISORDERS MEDLAB IP PTY LTD (AU) 2017-11-02 — — US claimed
EP-3212191-A1 TREATMENT FOR DEPRESSION AND DEPRESSIVE DISORDERS Medlab IP Pty Ltd. (AU) 2017-09-06 — — EP claimed
WO-2016065419-A1 TREATMENT FOR DEPRESSION AND DEPRESSIVE DISORDERS MEDLAB IP PTY LTD (AU) 2016-05-06 — — WO claimed
US-20150335688-A1 PROBIOTIC COMBINATIONS AND USES THEREOF MEDLAB IP PTY LTD (AU) 2015-11-26 — — US claimed
US-20120020945-A1 Food Supplement and Method for Enhancing Athletic Performance NUTRITIONAL ERGOGENIC SYSTEMS (US) 2012-01-26 — — US claimed
US-8067537-B2 Composition and method for treatment of stomatitis KYOWA HAKKO BIO CO., LTD. (JP) 2011-11-29 — — US claimed
US-20090285912-A1 Food Supplement and Method for Enhancing Athletic Performance NUTRITIONAL ERGOGENIC SYSTEMS 2009-11-19 — — US claimed
US-4738856-A Beverage and method for making a beverage for the nutritional supplementation of calcium in humans NUTRITION TECHNOLOGIES, INC. (US) 1988-04-19 — — US claimed
EP-0246177-A2 A beverage and method for making a beverage for the nutritional supplementation of calcium in humans Clark, George H. (US) 1987-11-19 — — EP claimed
EP-0202106-A2 A beverage and method of making a beverage for the replacement of body fluids and electrolytes Clark, George H. (US) 1986-11-20 — — EP claimed
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