Orotic Acid

Orotic Acid

SCHEMBL161885

O=C(O)c1cc(=O)[nH]c(=O)[nH]1.[LiH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.95
▸ LMNA P02545 1/20 0.95
▸ CYP2C19 P33261 2/20 0.61
▸ CYP1A2 P05177 2/20 0.57
▸ ALOX15 P16050 1/20 0.54
▸ NFKB1 P19838 1/20 0.54
▸ BLM P54132 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ TSHR P16473 2/20 0.47
▸ GPR84 Q9NQS5 4/20 0.45
▸ KDM4E B2RXH2 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ GPR35 Q9HC97 2/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ GRIN2D O15399 1/20 0.44
▸ GRIN3B O60391 1/20 0.44
▸ GLA P06280 1/20 0.44
▸ GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orotic Acid SCHEMBL29394966 0.98 ALDH1A1 (1.00) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL431534 0.98 ALDH1A1 (1.00) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL20865 0.98 ALDH1A1 (1.00) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL366203 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL16916880 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL23859825 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL11903511 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL9726379 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL1852415 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15
Orotic Acid SCHEMBL16194627 0.95 ALDH1A1 (0.95) ALDH1A1LMNACYP2C19CYP1A2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 678 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031707-A Composite targeting medicine for targeted alleviation of Alzheimer disease 陈小军 2026-05-15 — — CN claimed
EP-4735120-A2 CHEMICALLY INDUCED REPROGRAMMING TO REVERSE AGING President and Fellows of Harvard College (US) 2026-05-06 — — EP claimed
US-20260071247-A1 PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH TETS VICTOR (US) 2026-03-12 — — US claimed
US-20260071249-A1 PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH TETS VICTOR (US) 2026-03-12 — — US claimed
EP-4659754-A1 USE OF LITHIUM-CONTAINING COMPOUNDS IN TREATMENT OF TUMORS Institute of Basic Medical Sciences Chinese Academy of Medical Sciences (CN) 2025-12-10 — — EP claimed
US-20250345362-A1 MULTI-IONIC COMPLEX FOR THE PREVENTION OR TREATMENT OF INFLAMMATION YNIOS PHARMA (BE) 2025-11-13 — — US claimed
US-20250276008-A1 USE OF LITHIUM-CONTAINING COMPOUNDS IN TREATMENT OF TUMORS INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2025-09-04 — — US claimed
US-20250228889-A1 METHODS AND COMPOSITIONS FOR TREATING HEART CONDITIONS LUENINGHOENER CATHERINE (US) 2025-07-17 — — US claimed
WO-2025064524-A1 CONTAMINANT PRECIPITATION COMPOSITIONS AND METHODS OF USE LOCUS SOLUTIONS IPCO, LLC (US) 2025-03-27 — — WO claimed
EP-4525889-A1 MULTI-IONIC COMPLEX FOR THE PREVENTION OR TREATMENT OF INFLAMMATION YNIOS Pharma (BE) 2025-03-26 — — EP claimed
US-5223271-A Topical; combatting molluscum contagiosum; skin lesions EFAMOL HOLDINGS PLC (GB) 1993-06-29 — — US claimed
EP-0484112-A2 Use of lithium in the treatment or prophylaxis of Molluscum contagiosum SCOTIA HOLDINGS PLC (GB) 1992-05-06 — — EP claimed
US-5080909-A Lithium Salt, Vidarabine, Synergistic EFAMOL LIMITED (GB) 1992-01-14 — — US claimed
EP-0432700-A2 Use of lithium compounds for the treatment of combination skin EFAMOL HOLDINGS PLC (GB) 1991-06-19 — — EP claimed
EP-0132126-B1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF THE SKIN SCOTIA PHARMACEUTICALS LIMITED (GB) 1991-04-10 — — EP claimed
EP-0135312-B1 ANTI-VIRAL COMPOSITIONS SCOTIA PHARMACEUTICALS LIMITED (GB) 1989-12-27 — — EP claimed
US-4886670-A LITHIUM SALT AND ACYLCLOVIR; TOPICAL; HERPES EFAMOL LIMITED (GB) 1989-12-12 — — US claimed
EP-0305097-A2 Nutritional supplement SCOTIA HOLDINGS PLC (GB) 1989-03-01 — — EP claimed
EP-0135312-A2 Anti-viral compositions SCOTIA PHARMACEUTICALS LIMITED (GB) 1985-03-27 — — EP claimed
EP-0132126-A1 Methods and compositions for the treatment of the skin SCOTIA PHARMACEUTICALS LIMITED (GB) 1985-01-23 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071249-A1 PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH EIF2A, EIF6, TUFM ALDH1A1 4636/4885LMNA 2991/4885CYP2C19 4413/4885
US-20260071247-A1 PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH AMPD1, TUFM, AMPD3 ALDH1A1 4680/4885LMNA 2516/4885CYP2C19 4223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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