Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | CBLB | Q13191 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940183 | 0.86 | KDM5A (0.52) | CTSVCTSLCTSBCTSSCTSA | |
| SCHEMBL30740531 | 0.86 | KDM5A (0.52) | CTSVCTSLCTSBCTSSCTSA | |
| SCHEMBL6162351 | 0.82 | DGAT2 (0.49) | CTSVCTSLCTSBCTSSCTSA | |
| SCHEMBL6612788 | 0.80 | CTSV (0.51) | CTSVCTSLCTSBCTSSCTSA | |
| SCHEMBL30949272 | 0.79 | CTSA (0.40) | CTSVCTSLCTSBCTSSCTSA | |
| SCHEMBL3342644 | 0.78 | ALDH1A1 (0.52) | FYNCTSAMAP2K4PARP1BAZ2B | |
| SCHEMBL980384 | 0.76 | PIK3CD (0.50) | CTSAPIK3CDBRD4PIK3CAPIK3CB | |
| SCHEMBL20817541 | 0.76 | NT5E (0.63) | FYNCTSAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL30797840 | 0.76 | NT5E (0.63) | FYNCTSAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3344435 | 0.75 | PKMYT1 (0.47) | TLR8PIK3CDBRD4PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386951-A1 | PHENYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS | H. Hoffnabb-La Roche Ag (CH) | 2018-10-17 | — | — | EP | claimed |
| WO-2017097732-A1 | PHENYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-15 | — | — | WO | claimed |
| US-8642788-B2 | Activators of executioner procaspases 3, 6 and 7 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-02-04 | — | — | US | disclosed |
| CN-101965189-A | Activators of pro-caspase 3, 6 and 7 | UNIV CALIFORNIA | 2011-02-02 | — | — | CN | disclosed |
| EP-2237784-A1 | ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 | The Regents of the University of California (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009089508-A1 | ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-07-16 | — | — | WO | disclosed |