SCHEMBL3662391

SCHEMBL3662391

CCC#CCCOc1cccc(NC)c1F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.33
CHRM2 P08172 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 1/20 0.33
CHRM1 P11229 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
KCNH2 Q12809 1/20 0.33
HIF1A Q16665 1/20 0.33
HTR1B P28222 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTR1D P28221 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NCF1 P14598 1/20 0.31
SLC6A4 P31645 2/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3662361 0.93 L3MBTL1 (0.35) APPCHRM2L3MBTL1LMNACHRM1
SCHEMBL3659801 0.92 L3MBTL1 (0.37) APPCHRM2L3MBTL1LMNACHRM1
SCHEMBL3661720 0.91 PTPN1 (0.33) APPL3MBTL1LMNAHTR1BCYP1A2
SCHEMBL3658303 0.89 PPARG (0.36) L3MBTL1TSHRHTR1BCYP1A2CYP2C19
SCHEMBL3659956 0.87 APP (0.33) APPL3MBTL1LMNAHTR1BTDP1
SCHEMBL3656186 0.85 APP (0.34) APPL3MBTL1CYP1A2ALDH1A1
SCHEMBL3664058 0.84 L3MBTL1 (0.35) APPL3MBTL1TSHRHTR1BCYP1A2
SCHEMBL3662356 0.82 APP (0.34) APPL3MBTL1HTR1BCYP1A2CYP2D6
SCHEMBL3664404 0.80 SMN1; SMN2 (0.34) APPL3MBTL1HTR1BTDP1HTR1D
SCHEMBL3656907 0.80 PTGS2 (0.34) APPL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 APP 2380/4885CHRM2 140/4885L3MBTL1 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.