SCHEMBL3663273

SCHEMBL3663273

CCCOc1ccc(F)c2c(=O)c(I)c[nH]c12.CCCOc1ccc(F)c2c(=O)cc[nH]c12

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 1/20 0.30
SCN10A Q9Y5Y9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1136317 0.92 PDE4D (0.33)
SCHEMBL1136128 0.88 CCR8 (0.36) SCN8ASCN10A
SCHEMBL1136122 0.73 BRD4 (0.37)
SCHEMBL1136344 0.72 PDE5A (0.34)
SCHEMBL1136230 0.72 MGAM (0.40)
SCHEMBL1136266 0.72 MET (0.38)
SCHEMBL2491967 0.72 ALDH1A1 (0.38)
SCHEMBL1135921 0.72 GCGR (0.39)
SCHEMBL1136358 0.72 PDE5A (0.39)
SCHEMBL1136154 0.72 PTPN11 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152699-A1 QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION Otsuka Pharmaceutical Co., Ltd. (JP) 2010-02-17 EP disclosed
WO-2008150029-A1 QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-12-11 WO disclosed