SCHEMBL2491967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136335	0.89	TDO2 (0.40)	ALDH1A1PKMPDE5AMETCTSD
	SCHEMBL1135921	0.89	GCGR (0.39)	ALDH1A1PKMCCNT1CCNA2CDK2
	SCHEMBL1136264	0.85	TDO2 (0.47)	ALDH1A1PKMCCNA2CDK2MET
	SCHEMBL1136266	0.84	MET (0.38)	ALDH1A1PKMCDK2METKDR
	SCHEMBL1136230	0.84	MGAM (0.40)	ALDH1A1PKMCDK2METKDR
	SCHEMBL2491640	0.84	BRD4 (0.42)	ALDH1A1PKMROCK2ROCK1CDC42BPB
	SCHEMBL1136343	0.83	FFAR4 (0.40)	ALDH1A1PKMMETKDRNPC1
	SCHEMBL1136119	0.83	MAOB (0.40)	ALDH1A1METKDRNPC1RAB9A
	SCHEMBL2492033	0.82	MET (0.41)	CDK2METKDRNPC1RAB9A
	SCHEMBL1136274	0.82	ALDH1A1 (0.33)	ALDH1A1PKMPDE5ACCNT1CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.